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Nicotine causes thickening of the blood vessels, which hampers the blood flow and also causes high blood pressure or hypertension, Mukesh Goel, Senior Consultant, Cardio Thoracic & Vascular Surgery at Indraprastha Apollo Hospitals, told IANS

Moreover, nicotine suppresses M1 microglia cell differentiation and decreases TNF- release from these cells, impairs Th1 and th17 cells differentiation which consequently resulted to the protection of neurons [231]

Around one in 20 adults in England uses e-cigarettes, and nearly all of these are ex-smokers or current smokers who are trying to cut down or quit